How to write a good scientific review article

Affiliation.

  • 1 The FEBS Journal Editorial Office, Cambridge, UK.
  • PMID: 35792782
  • DOI: 10.1111/febs.16565

Literature reviews are valuable resources for the scientific community. With research accelerating at an unprecedented speed in recent years and more and more original papers being published, review articles have become increasingly important as a means to keep up to date with developments in a particular area of research. A good review article provides readers with an in-depth understanding of a field and highlights key gaps and challenges to address with future research. Writing a review article also helps to expand the writer's knowledge of their specialist area and to develop their analytical and communication skills, amongst other benefits. Thus, the importance of building review-writing into a scientific career cannot be overstated. In this instalment of The FEBS Journal's Words of Advice series, I provide detailed guidance on planning and writing an informative and engaging literature review.

© 2022 Federation of European Biochemical Societies.

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How to Write a Peer Review

how to start writing a scientific review paper

When you write a peer review for a manuscript, what should you include in your comments? What should you leave out? And how should the review be formatted?

This guide provides quick tips for writing and organizing your reviewer report.

Review Outline

Use an outline for your reviewer report so it’s easy for the editors and author to follow. This will also help you keep your comments organized.

Think about structuring your review like an inverted pyramid. Put the most important information at the top, followed by details and examples in the center, and any additional points at the very bottom.

how to start writing a scientific review paper

Here’s how your outline might look:

1. Summary of the research and your overall impression

In your own words, summarize what the manuscript claims to report. This shows the editor how you interpreted the manuscript and will highlight any major differences in perspective between you and the other reviewers. Give an overview of the manuscript’s strengths and weaknesses. Think about this as your “take-home” message for the editors. End this section with your recommended course of action.

2. Discussion of specific areas for improvement

It’s helpful to divide this section into two parts: one for major issues and one for minor issues. Within each section, you can talk about the biggest issues first or go systematically figure-by-figure or claim-by-claim. Number each item so that your points are easy to follow (this will also make it easier for the authors to respond to each point). Refer to specific lines, pages, sections, or figure and table numbers so the authors (and editors) know exactly what you’re talking about.

Major vs. minor issues

What’s the difference between a major and minor issue? Major issues should consist of the essential points the authors need to address before the manuscript can proceed. Make sure you focus on what is  fundamental for the current study . In other words, it’s not helpful to recommend additional work that would be considered the “next step” in the study. Minor issues are still important but typically will not affect the overall conclusions of the manuscript. Here are some examples of what would might go in the “minor” category:

  • Missing references (but depending on what is missing, this could also be a major issue)
  • Technical clarifications (e.g., the authors should clarify how a reagent works)
  • Data presentation (e.g., the authors should present p-values differently)
  • Typos, spelling, grammar, and phrasing issues

3. Any other points

Confidential comments for the editors.

Some journals have a space for reviewers to enter confidential comments about the manuscript. Use this space to mention concerns about the submission that you’d want the editors to consider before sharing your feedback with the authors, such as concerns about ethical guidelines or language quality. Any serious issues should be raised directly and immediately with the journal as well.

This section is also where you will disclose any potentially competing interests, and mention whether you’re willing to look at a revised version of the manuscript.

Do not use this space to critique the manuscript, since comments entered here will not be passed along to the authors.  If you’re not sure what should go in the confidential comments, read the reviewer instructions or check with the journal first before submitting your review. If you are reviewing for a journal that does not offer a space for confidential comments, consider writing to the editorial office directly with your concerns.

Get this outline in a template

Giving Feedback

Giving feedback is hard. Giving effective feedback can be even more challenging. Remember that your ultimate goal is to discuss what the authors would need to do in order to qualify for publication. The point is not to nitpick every piece of the manuscript. Your focus should be on providing constructive and critical feedback that the authors can use to improve their study.

If you’ve ever had your own work reviewed, you already know that it’s not always easy to receive feedback. Follow the golden rule: Write the type of review you’d want to receive if you were the author. Even if you decide not to identify yourself in the review, you should write comments that you would be comfortable signing your name to.

In your comments, use phrases like “ the authors’ discussion of X” instead of “ your discussion of X .” This will depersonalize the feedback and keep the focus on the manuscript instead of the authors.

General guidelines for effective feedback

how to start writing a scientific review paper

  • Justify your recommendation with concrete evidence and specific examples.
  • Be specific so the authors know what they need to do to improve.
  • Be thorough. This might be the only time you read the manuscript.
  • Be professional and respectful. The authors will be reading these comments too.
  • Remember to say what you liked about the manuscript!

how to start writing a scientific review paper

Don’t

  • Recommend additional experiments or  unnecessary elements that are out of scope for the study or for the journal criteria.
  • Tell the authors exactly how to revise their manuscript—you don’t need to do their work for them.
  • Use the review to promote your own research or hypotheses.
  • Focus on typos and grammar. If the manuscript needs significant editing for language and writing quality, just mention this in your comments.
  • Submit your review without proofreading it and checking everything one more time.

Before and After: Sample Reviewer Comments

Keeping in mind the guidelines above, how do you put your thoughts into words? Here are some sample “before” and “after” reviewer comments

✗ Before

“The authors appear to have no idea what they are talking about. I don’t think they have read any of the literature on this topic.”

✓ After

“The study fails to address how the findings relate to previous research in this area. The authors should rewrite their Introduction and Discussion to reference the related literature, especially recently published work such as Darwin et al.”

“The writing is so bad, it is practically unreadable. I could barely bring myself to finish it.”

“While the study appears to be sound, the language is unclear, making it difficult to follow. I advise the authors work with a writing coach or copyeditor to improve the flow and readability of the text.”

“It’s obvious that this type of experiment should have been included. I have no idea why the authors didn’t use it. This is a big mistake.”

“The authors are off to a good start, however, this study requires additional experiments, particularly [type of experiment]. Alternatively, the authors should include more information that clarifies and justifies their choice of methods.”

Suggested Language for Tricky Situations

You might find yourself in a situation where you’re not sure how to explain the problem or provide feedback in a constructive and respectful way. Here is some suggested language for common issues you might experience.

What you think : The manuscript is fatally flawed. What you could say: “The study does not appear to be sound” or “the authors have missed something crucial”.

What you think : You don’t completely understand the manuscript. What you could say : “The authors should clarify the following sections to avoid confusion…”

What you think : The technical details don’t make sense. What you could say : “The technical details should be expanded and clarified to ensure that readers understand exactly what the researchers studied.”

What you think: The writing is terrible. What you could say : “The authors should revise the language to improve readability.”

What you think : The authors have over-interpreted the findings. What you could say : “The authors aim to demonstrate [XYZ], however, the data does not fully support this conclusion. Specifically…”

What does a good review look like?

Check out the peer review examples at F1000 Research to see how other reviewers write up their reports and give constructive feedback to authors.

Time to Submit the Review!

Be sure you turn in your report on time. Need an extension? Tell the journal so that they know what to expect. If you need a lot of extra time, the journal might need to contact other reviewers or notify the author about the delay.

Tip: Building a relationship with an editor

You’ll be more likely to be asked to review again if you provide high-quality feedback and if you turn in the review on time. Especially if it’s your first review for a journal, it’s important to show that you are reliable. Prove yourself once and you’ll get asked to review again!

  • Getting started as a reviewer
  • Responding to an invitation
  • Reading a manuscript
  • Writing a peer review

The contents of the Peer Review Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

The contents of the Writing Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

There’s a lot to consider when deciding where to submit your work. Learn how to choose a journal that will help your study reach its audience, while reflecting your values as a researcher…

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Article Contents

Introduction, selection of a topic, scientific literature search and analysis, structure of a scientific review article, tips for success, acknowledgments, conflict of interest statement.

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A Step-by-Step Guide to Writing a Scientific Review Article

  • Article contents
  • Figures & tables
  • Supplementary Data

Manisha Bahl, A Step-by-Step Guide to Writing a Scientific Review Article, Journal of Breast Imaging , Volume 5, Issue 4, July/August 2023, Pages 480–485, https://doi.org/10.1093/jbi/wbad028

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Scientific review articles are comprehensive, focused reviews of the scientific literature written by subject matter experts. The task of writing a scientific review article can seem overwhelming; however, it can be managed by using an organized approach and devoting sufficient time to the process. The process involves selecting a topic about which the authors are knowledgeable and enthusiastic, conducting a literature search and critical analysis of the literature, and writing the article, which is composed of an abstract, introduction, body, and conclusion, with accompanying tables and figures. This article, which focuses on the narrative or traditional literature review, is intended to serve as a guide with practical steps for new writers. Tips for success are also discussed, including selecting a focused topic, maintaining objectivity and balance while writing, avoiding tedious data presentation in a laundry list format, moving from descriptions of the literature to critical analysis, avoiding simplistic conclusions, and budgeting time for the overall process.

Scientific review articles provide a focused and comprehensive review of the available evidence about a subject, explain the current state of knowledge, and identify gaps that could be topics for potential future research.

Detailed tables reviewing the relevant scientific literature are important components of high-quality scientific review articles.

Tips for success include selecting a focused topic, maintaining objectivity and balance, avoiding tedious data presentation, providing a critical analysis rather than only a description of the literature, avoiding simplistic conclusions, and budgeting time for the overall process.

The process of researching and writing a scientific review article can be a seemingly daunting task but can be made manageable, and even enjoyable, if an organized approach is used and a reasonable timeline is given. Scientific review articles provide authors with an opportunity to synthesize the available evidence about a specific subject, contribute their insights to the field, and identify opportunities for future research. The authors, in turn, gain recognition as subject matter experts and thought leaders in the field. An additional benefit to the authors is that high-quality review articles can often be cited many years after publication ( 1 , 2 ). The reader of a scientific review article should gain an understanding of the current state of knowledge on the subject, points of controversy, and research questions that have yet to be answered ( 3 ).

There are two types of review articles, narrative or traditional literature reviews and systematic reviews, which may or may not be accompanied by a meta-analysis ( 4 ). This article, which focuses on the narrative or traditional literature review, is intended to serve as a guide with practical steps for new writers. It is geared toward breast imaging radiologists who are preparing to write a scientific review article for the Journal of Breast Imaging but can also be used by any writer, reviewer, or reader. In the narrative or traditional literature review, the available scientific literature is synthesized and no new data are presented. This article first discusses the process of selecting an appropriate topic. Then, practical tips for conducting a literature search and analyzing the literature are provided. The structure of a scientific review article is outlined and tips for success are described.

Scientific review articles are often solicited by journal editors and written by experts in the field. For solicited or invited articles, a senior expert in the field may be contacted and, in turn, may ask junior faculty or trainees to help with the literature search and writing process. Most journals also consider proposals for review article topics. The journal’s editorial office can be contacted via e-mail with a topic proposal, ideally with an accompanying outline or an extended abstract to help explain the proposal.

When selecting a topic for a scientific review article, the following considerations should be taken into account: The authors should be knowledgeable about and interested in the topic; the journal’s audience should be interested in the topic; and the topic should be focused, with a sufficient number of current research studies ( Figure 1 ). For the Journal of Breast Imaging , a scientific review article on breast MRI would be too broad in scope. Examples of more focused topics include abbreviated breast MRI ( 5 ), concerns about gadolinium deposition in the setting of screening MRI ( 6 ), Breast Imaging Reporting and Data System (BI-RADS) 3 assessments on MRI ( 7 , 8 ), the science of background parenchymal enhancement ( 9 ), and screening MRI in women at intermediate risk ( 10 ).

Summary of the factors to consider when selecting a topic for a scientific review article. Adapted with permission from Dhillon et al (2).

Summary of the factors to consider when selecting a topic for a scientific review article. Adapted with permission from Dhillon et al ( 2 ).

Once a well-defined topic is selected, the next step is to conduct a literature search. There are multiple indexing databases that can be used for a literature search, including PubMed, SCOPUS, and Web of Science ( 11–13 ). A list of databases with links can be found on the National Institutes of Health website ( 14 ). It is advised to keep track of the search terms that are used so that the search could be replicated if needed.

While reading articles, taking notes and keeping track of findings in a spreadsheet or database can be helpful. The following points should be considered for each article: What is the purpose of the article, and is it relevant to the review article topic? What was the study design (eg, retrospective analysis, randomized controlled trial)? Are the conclusions that are drawn based on the presented data valid and reasonable? What are the strengths and limitations of the study? In the discussion section, do the authors discuss other literature that both supports and contradicts their findings? It can also be helpful to read accompanying editorials, if available, that are written by experts to explain the importance of the original scientific article in the context of other work in the field.

If previous review articles on the same topic are discovered during the literature search, then the following strategies could be considered: discussing approaches used and limitations of past reviews, identifying a new angle that has not been previously covered, and/or focusing on new research that has been published since the most recent reviews on the topic ( 3 ). It is highly encouraged to create an outline and solicit feedback from co-authors before writing begins.

Writing a high-quality scientific review article is “a balancing act between the scientific rigor needed to select and critically appraise original studies, and the art of telling a story by providing context, exploring the known and the unknown, and pointing the way forward” ( 15 ). The ideal scientific review article is balanced and authoritative and serves as a definitive reference on the topic. Review articles tend to be 4000 to 5000 words in length, with 80% to 90% devoted to the body.

When preparing a scientific review article, writers can consider using the Scale for the Assessment of Narrative Review Articles, which has been proposed as a critical appraisal tool to help editors, reviewers, and readers assess non–systematic review articles ( 16 ). It is composed of the following six items, which are rated from 0 to 2 (with 0 being low quality and 2 being high quality): explanation of why the article is important, statement of aims or questions to be addressed, description of the literature search strategy, inclusion of appropriate references, scientific reasoning, and appropriate data presentation. In a study with three raters each reviewing 30 articles, the scale was felt to be feasible in daily editorial work and had high inter-rater reliability.

The components of a scientific review article include the abstract, introduction, body, conclusion, references, tables, and figures, which are described below.

Abstracts are typically structured as a single paragraph, ranging from 200 to 250 words in length. The abstract briefly explains why the topic is important, provides a summary of the main conclusions that are being drawn based on the research studies that were included and analyzed in the review article, and describes how the article is organized ( 17 ). Because the abstract should provide a summary of the main conclusions being drawn, it is often written last, after the other sections of the article have been completed. It does not include references.

The introduction provides detailed background about the topic and outlines the objectives of the review article. It is important to explain why the literature on that topic should be reviewed (eg, no prior reviews, different angle from prior reviews, new published research). The problem-gap-hook approach can be used, in which the topic is introduced, the gap is explained (eg, lack of published synthesis), and the hook (or why it matters) is provided ( 18 ). If there are prior review articles on the topic, particularly recent ones, then the authors are encouraged to justify how their review contributes to the existing literature. The content in the introduction section should be supported with references, but specific findings from recent research studies are typically not described, instead being discussed in depth in the body.

In a traditional or narrative review article, a methods section is optional. The methods section should include a list of the databases and years that were searched, search terms that were used, and a summary of the inclusion and exclusion criteria for articles ( 17 , 19 ).

The body can take different forms depending on the topic but should be organized into sections with subheadings, with each subsection having an independent introduction and conclusion. In the body, published studies should be reviewed in detail and in an organized fashion. In general, each paragraph should begin with a thesis statement or main point, and the sentences that follow it should consist of supporting evidence drawn from the literature. Research studies need not be discussed in chronological order, and the results from one research study may be discussed in different sections of the body. For example, if writing a scientific review article on screening digital breast tomosynthesis, cancer detection rates reported in one study may be discussed in a separate paragraph from the false-positive rates that were reported in the same study.

Emphasis should be placed on the significance of the study results in the broader context of the subject. The strengths and weaknesses of individual studies should be discussed. An example of this type of discussion is as follows: “Smith et al found no differences in re-excision rates among breast cancer patients who did and did not undergo preoperative MRI. However, there were several important limitations of this study. The radiologists were not required to have breast MRI interpretation experience, nor was it required that MRI-detected findings undergo biopsy prior to surgery.” Other examples of phrases that can be used for constructive criticism are available online ( 20 ).

The conclusion section ties everything together and clearly states the conclusions that are being drawn based on the research studies included and analyzed in the article. The authors are also encouraged to provide their views on future research, important challenges, and unanswered questions.

Scientific review articles tend to have a large number of supporting references (up to 100). When possible, referencing the original article (rather than a review article referring to the original article) is preferred. The use of a reference manager, such as EndNote (Clarivate, London, UK) ( 21 ), Mendeley Desktop (Elsevier, Amsterdam, the Netherlands) ( 22 ), Paperpile (Paperpile LLC, Cambridge, MA) ( 23 ), RefWorks (ProQuest, Ann Arbor, MI) ( 24 ), or Zotero (Corporation for Digital Scholarship, Fairfax, VA) ( 25 ), is highly encouraged, as it ensures appropriate reference ordering even when text is moved or added and can facilitate the switching of formats based on journal requirements ( 26 ).

Tables and Figures

The inclusion of tables and figures can improve the readability of the review. Detailed tables that review the scientific literature are expected ( Table 1 ). A table listing gaps in knowledge as potential areas for future research may also be included ( 17 ). Although scientific review articles are not expected to be as figure-rich as educational review articles, figures can be beneficial to illustrate complex concepts and summarize or synthesize relevant data ( Figure 2 ). Of note, if nonoriginal figures are used, permission from the copyright owner must be obtained.

Example of an Effective Table From a Scientific Review Article About Screening MRI in Women at Intermediate Risk of Breast Cancer.

Abbreviations: ADH, atypical ductal hyperplasia; ALH, atypical lobular hyperplasia; CDR, cancer detection rate; LCIS, lobular carcinoma in situ; NR, not reported; PPV, positive predictive value. NOTE: The Detailed Table Provides a Summary of the Relevant Scientific Literature on Screening MRI in women with lobular neoplasia or ADH. Adapted with permission from Bahl ( 10 ).

a The reported CDR is an incremental CDR in the studies by Friedlander et al and Chikarmane et al. In all studies, some, but not all, included patients had a prior MRI examination, so the reported CDR represents a combination of both the prevalent and incident CDRs.

b This study included 455 patients with LCIS (some of whom had concurrent ALH or ADH). Twenty-nine cancers were MRI-detected, and 115 benign biopsies were prompted by MRI findings.

Example of an effective figure from a scientific review article about breast cancer risk assessment. The figure provides a risk assessment algorithm for breast cancer. Reprinted with permission from Kim et al (28).

Example of an effective figure from a scientific review article about breast cancer risk assessment. The figure provides a risk assessment algorithm for breast cancer. Reprinted with permission from Kim et al ( 28 ).

Select a Focused but Broad Enough Topic

A common pitfall is to be too ambitious in scope, resulting in a very time-consuming literature search and superficial coverage of some aspects of the topic. The ideal topic should be focused enough to be manageable but with a large enough body of available research to justify the need for a review article. One article on the topic of scientific reviews suggests that at least 15 to 20 relevant research papers published within the previous five years should be easily identifiable to warrant writing a review article ( 2 ).

Provide a Summary of Main Conclusions in the Abstract

Another common pitfall is to only introduce the topic and provide a roadmap for the article in the abstract. The abstract should also provide a summary of the main conclusions that are being drawn based on the research studies that were included and analyzed in the review article.

Be Objective

The content and key points of the article should be based on the published scientific literature and not biased toward one’s personal opinion.

Avoid Tedious Data Presentation

Extensive lists of statements about the findings of other authors (eg, author A found Z, author B found Y, while author C found X, etc) make it difficult for the reader to understand and follow the article. It is best for the writing to be thematic based on research findings rather than author-centered ( 27 ). Each paragraph in the body should begin with a thesis statement or main point, and the sentences that follow should consist of supporting evidence drawn from the literature. For example, in a scientific review article about artificial intelligence (AI) for screening mammography, one approach would be to write that article A found a higher cancer detection rate, higher efficiency, and a lower false-positive rate with use of the AI algorithm and article B found a similar cancer detection rate and higher efficiency, while article C found a higher cancer detection rate and higher false-positive rate. Rather, a better approach would be to write one or more paragraphs summarizing the literature on cancer detection rates, one or more paragraphs on false-positive rates, and one or more paragraphs on efficiency. The results from one study (eg, article A) need not all be discussed in the same paragraph.

Move from Description (Summary) to Analysis

A common pitfall is to describe and summarize the published literature without providing a critical analysis. The purpose of the narrative or traditional review article is not only to summarize relevant discoveries but also to synthesize the literature, discuss its limitations and implications, and speculate on the future.

Avoid Simplistic Conclusions

The scientific review article’s conclusions should consider the complexity of the topic and the quality of the evidence. When describing a study’s findings, it is best to use language that reflects the quality of the evidence rather than making definitive statements. For example, rather than stating that “The use of preoperative breast MRI leads to a reduction in re-excision rates,” the following comments could be made: “Two single-institution retrospective studies found that preoperative MRI was associated with lower rates of positive surgical margins, which suggests that preoperative MRI may lead to reduced re-excision rates. Larger studies with randomization of patients are needed to validate these findings.”

Budget Time for Researching, Synthesizing, and Writing

The amount of time necessary to write a high-quality scientific review article can easily be underestimated. The process of searching for and synthesizing the scientific literature on a topic can take weeks to months to complete depending on the number of authors involved in this process.

Scientific review articles are common in the medical literature and can serve as definitive references on the topic for other scientists, clinicians, and trainees. The first step in the process of preparing a scientific review article is to select a focused topic. This step is followed by a literature search and critical analysis of the published data. The components of the article include an abstract, introduction, body, and conclusion, with the majority devoted to the body, in which the relevant literature is reviewed in detail. The article should be objective and balanced, with summaries and critical analysis of the available evidence. Budgeting time for researching, synthesizing, and writing; taking advantage of the resources listed in this article and available online; and soliciting feedback from co-authors at various stages of the process (eg, after an outline is created) can help new writers produce high-quality scientific review articles.

The author thanks Susanne L. Loomis (Medical and Scientific Communications, Strategic Communications, Department of Radiology, Massachusetts General Hospital, Boston, MA) for creating Figure 1 in this article.

None declared.

M.B. is a consultant for Lunit (medical AI software company) and an expert panelist for 2nd.MD (a digital health company). She also receives funding from the National Institutes of Health (K08CA241365). M.B. is an associate editor of the Journal of Breast Imaging . As such, she was excluded from the editorial process.

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  • 08 October 2018

How to write a thorough peer review

  • Mathew Stiller-Reeve 0

Mathew Stiller-Reeve is a climate researcher at NORCE/Bjerknes Centre for Climate Research in Bergen, Norway, the leader of SciSnack.com, and a thematic editor at Geoscience Communication .

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Scientists do not receive enough peer-review training. To improve this situation, a small group of editors and I developed a peer-review workflow to guide reviewers in delivering useful and thorough analyses that can really help authors to improve their papers.

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doi: https://doi.org/10.1038/d41586-018-06991-0

This is an article from the Nature Careers Community, a place for Nature readers to share their professional experiences and advice. Guest posts are encouraged. You can get in touch with the editor at [email protected].

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Writing a good review article

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Table of Contents

As a young researcher, you might wonder how to start writing your first review article, and the extent of the information that it should contain. A review article is a comprehensive summary of the current understanding of a specific research topic and is based on previously published research. Unlike research papers, it does not contain new results, but can propose new inferences based on the combined findings of previous research.

Types of review articles

Review articles are typically of three types: literature reviews, systematic reviews, and meta-analyses.

A literature review is a general survey of the research topic and aims to provide a reliable and unbiased account of the current understanding of the topic.

A systematic review , in contrast, is more specific and attempts to address a highly focused research question. Its presentation is more detailed, with information on the search strategy used, the eligibility criteria for inclusion of studies, the methods utilized to review the collected information, and more.

A meta-analysis is similar to a systematic review in that both are systematically conducted with a properly defined research question. However, unlike the latter, a meta-analysis compares and evaluates a defined number of similar studies. It is quantitative in nature and can help assess contrasting study findings.

Tips for writing a good review article

Here are a few practices that can make the time-consuming process of writing a review article easier:

  • Define your question: Take your time to identify the research question and carefully articulate the topic of your review paper. A good review should also add something new to the field in terms of a hypothesis, inference, or conclusion. A carefully defined scientific question will give you more clarity in determining the novelty of your inferences.
  • Identify credible sources: Identify relevant as well as credible studies that you can base your review on, with the help of multiple databases or search engines. It is also a good idea to conduct another search once you have finished your article to avoid missing relevant studies published during the course of your writing.
  • Take notes: A literature search involves extensive reading, which can make it difficult to recall relevant information subsequently. Therefore, make notes while conducting the literature search and note down the source references. This will ensure that you have sufficient information to start with when you finally get to writing.
  • Describe the title, abstract, and introduction: A good starting point to begin structuring your review is by drafting the title, abstract, and introduction. Explicitly writing down what your review aims to address in the field will help shape the rest of your article.
  • Be unbiased and critical: Evaluate every piece of evidence in a critical but unbiased manner. This will help you present a proper assessment and a critical discussion in your article.
  • Include a good summary: End by stating the take-home message and identify the limitations of existing studies that need to be addressed through future studies.
  • Ask for feedback: Ask a colleague to provide feedback on both the content and the language or tone of your article before you submit it.
  • Check your journal’s guidelines: Some journals only publish reviews, while some only publish research articles. Further, all journals clearly indicate their aims and scope. Therefore, make sure to check the appropriateness of a journal before submitting your article.

Writing review articles, especially systematic reviews or meta-analyses, can seem like a daunting task. However, Elsevier Author Services can guide you by providing useful tips on how to write an impressive review article that stands out and gets published!

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7 Writing a Literature Review

Hundreds of original investigation research articles on health science topics are published each year. It is becoming harder and harder to keep on top of all new findings in a topic area and – more importantly – to work out how they all fit together to determine our current understanding of a topic. This is where literature reviews come in.

In this chapter, we explain what a literature review is and outline the stages involved in writing one. We also provide practical tips on how to communicate the results of a review of current literature on a topic in the format of a literature review.

7.1 What is a literature review?

Screenshot of journal article

Literature reviews provide a synthesis and evaluation  of the existing literature on a particular topic with the aim of gaining a new, deeper understanding of the topic.

Published literature reviews are typically written by scientists who are experts in that particular area of science. Usually, they will be widely published as authors of their own original work, making them highly qualified to author a literature review.

However, literature reviews are still subject to peer review before being published. Literature reviews provide an important bridge between the expert scientific community and many other communities, such as science journalists, teachers, and medical and allied health professionals. When the most up-to-date knowledge reaches such audiences, it is more likely that this information will find its way to the general public. When this happens, – the ultimate good of science can be realised.

A literature review is structured differently from an original research article. It is developed based on themes, rather than stages of the scientific method.

In the article Ten simple rules for writing a literature review , Marco Pautasso explains the importance of literature reviews:

Literature reviews are in great demand in most scientific fields. Their need stems from the ever-increasing output of scientific publications. For example, compared to 1991, in 2008 three, eight, and forty times more papers were indexed in Web of Science on malaria, obesity, and biodiversity, respectively. Given such mountains of papers, scientists cannot be expected to examine in detail every single new paper relevant to their interests. Thus, it is both advantageous and necessary to rely on regular summaries of the recent literature. Although recognition for scientists mainly comes from primary research, timely literature reviews can lead to new synthetic insights and are often widely read. For such summaries to be useful, however, they need to be compiled in a professional way (Pautasso, 2013, para. 1).

An example of a literature review is shown in Figure 7.1.

Video 7.1: What is a literature review? [2 mins, 11 secs]

Watch this video created by Steely Library at Northern Kentucky Library called ‘ What is a literature review? Note: Closed captions are available by clicking on the CC button below.

Examples of published literature reviews

  • Strength training alone, exercise therapy alone, and exercise therapy with passive manual mobilisation each reduce pain and disability in people with knee osteoarthritis: a systematic review
  • Traveler’s diarrhea: a clinical review
  • Cultural concepts of distress and psychiatric disorders: literature review and research recommendations for global mental health epidemiology

7.2 Steps of writing a literature review

Writing a literature review is a very challenging task. Figure 7.2 summarises the steps of writing a literature review. Depending on why you are writing your literature review, you may be given a topic area, or may choose a topic that particularly interests you or is related to a research project that you wish to undertake.

Chapter 6 provides instructions on finding scientific literature that would form the basis for your literature review.

Once you have your topic and have accessed the literature, the next stages (analysis, synthesis and evaluation) are challenging. Next, we look at these important cognitive skills student scientists will need to develop and employ to successfully write a literature review, and provide some guidance for navigating these stages.

Steps of writing a ltierature review which include: research, synthesise, read abstracts, read papers, evaualte findings and write

Analysis, synthesis and evaluation

Analysis, synthesis and evaluation are three essential skills required by scientists  and you will need to develop these skills if you are to write a good literature review ( Figure 7.3 ). These important cognitive skills are discussed in more detail in Chapter 9.

Diagram with the words analysis, synthesis and evaluation. Under analysis it says taking a process or thing and breaking it down. Under synthesis it says combining elements of separate material and under evaluation it says critiquing a product or process

The first step in writing a literature review is to analyse the original investigation research papers that you have gathered related to your topic.

Analysis requires examining the papers methodically and in detail, so you can understand and interpret aspects of the study described in each research article.

An analysis grid is a simple tool you can use to help with the careful examination and breakdown of each paper. This tool will allow you to create a concise summary of each research paper; see Table 7.1 for an example of  an analysis grid. When filling in the grid, the aim is to draw out key aspects of each research paper. Use a different row for each paper, and a different column for each aspect of the paper ( Tables 7.2 and 7.3 show how completed analysis grid may look).

Before completing your own grid, look at these examples and note the types of information that have been included, as well as the level of detail. Completing an analysis grid with a sufficient level of detail will help you to complete the synthesis and evaluation stages effectively. This grid will allow you to more easily observe similarities and differences across the findings of the research papers and to identify possible explanations (e.g., differences in methodologies employed) for observed differences between the findings of different research papers.

Table 7.1: Example of an analysis grid

A tab;e split into columns with annotated comments

Table 7.3: Sample filled-in analysis grid for research article by Ping and colleagues

Source: Ping, WC, Keong, CC & Bandyopadhyay, A 2010, ‘Effects of acute supplementation of caffeine on cardiorespiratory responses during endurance running in a hot and humid climate’, Indian Journal of Medical Research, vol. 132, pp. 36–41. Used under a CC-BY-NC-SA licence.

Step two of writing a literature review is synthesis.

Synthesis describes combining separate components or elements to form a connected whole.

You will use the results of your analysis to find themes to build your literature review around. Each of the themes identified will become a subheading within the body of your literature review.

A good place to start when identifying themes is with the dependent variables (results/findings) that were investigated in the research studies.

Because all of the research articles you are incorporating into your literature review are related to your topic, it is likely that they have similar study designs and have measured similar dependent variables. Review the ‘Results’ column of your analysis grid. You may like to collate the common themes in a synthesis grid (see, for example Table 7.4 ).

Table showing themes of the article including running performance, rating of perceived exertion, heart rate and oxygen uptake

Step three of writing a literature review is evaluation, which can only be done after carefully analysing your research papers and synthesising the common themes (findings).

During the evaluation stage, you are making judgements on the themes presented in the research articles that you have read. This includes providing physiological explanations for the findings. It may be useful to refer to the discussion section of published original investigation research papers, or another literature review, where the authors may mention tested or hypothetical physiological mechanisms that may explain their findings.

When the findings of the investigations related to a particular theme are inconsistent (e.g., one study shows that caffeine effects performance and another study shows that caffeine had no effect on performance) you should attempt to provide explanations of why the results differ, including physiological explanations. A good place to start is by comparing the methodologies to determine if there are any differences that may explain the differences in the findings (see the ‘Experimental design’ column of your analysis grid). An example of evaluation is shown in the examples that follow in this section, under ‘Running performance’ and ‘RPE ratings’.

When the findings of the papers related to a particular theme are consistent (e.g., caffeine had no effect on oxygen uptake in both studies) an evaluation should include an explanation of why the results are similar. Once again, include physiological explanations. It is still a good idea to compare methodologies as a background to the evaluation. An example of evaluation is shown in the following under ‘Oxygen consumption’.

Annotated paragraphs on running performance with annotated notes such as physiological explanation provided; possible explanation for inconsistent results

7.3 Writing your literature review

Once you have completed the analysis, and synthesis grids and written your evaluation of the research papers , you can combine synthesis and evaluation information to create a paragraph for a literature review ( Figure 7.4 ).

Bubble daigram showing connection between synethesis, evaulation and writing a paragraph

The following paragraphs are an example of combining the outcome of the synthesis and evaluation stages to produce a paragraph for a literature review.

Note that this is an example using only two papers – most literature reviews would be presenting information on many more papers than this ( (e.g., 106 papers in the review article by Bain and colleagues discussed later in this chapter). However, the same principle applies regardless of the number of papers reviewed.

Introduction paragraph showing where evaluation occurs

The next part of this chapter looks at the each section of a literature review and explains how to write them by referring to a review article that was published in Frontiers in Physiology and shown in Figure 7.1. Each section from the published article is annotated to highlight important features of the format of the review article, and identifies the synthesis and evaluation information.

In the examination of each review article section we will point out examples of how the authors have presented certain information and where they display application of important cognitive processes; we will use the colour code shown below:

Colour legend

This should be one paragraph that accurately reflects the contents of the review article.

An annotated abstract divided into relevant background information, identification of the problem, summary of recent literature on topic, purpose of the review

Introduction

The introduction should establish the context and importance of the review

An annotated introduction divided into relevant background information, identification of the issue and overview of points covered

Body of literature review

Annotated body of literature review with following comments annotated on the side: subheadings are included to separate body of review into themes; introductory sentences with general background information; identification of gap in current knowledge; relevant theoretical background information; syntheis of literature relating to the potential importance of cerebral metabolism; an evaluation; identification of gaps in knowledge; synthesis of findings related to human studies; author evaluation

The reference section provides a list of the references that you cited in the body of your review article. The format will depend on the journal of publication as each journal has their own specific referencing format.

It is important to accurately cite references in research papers to acknowledge your sources and ensure credit is appropriately given to authors of work you have referred to. An accurate and comprehensive reference list also shows your readers that you are well-read in your topic area and are aware of the key papers that provide the context to your research.

It is important to keep track of your resources and to reference them consistently in the format required by the publication in which your work will appear. Most scientists will use reference management software to store details of all of the journal articles (and other sources) they use while writing their review article. This software also automates the process of adding in-text references and creating a reference list. In the review article by Bain et al. (2014) used as an example in this chapter, the reference list contains 106 items, so you can imagine how much help referencing software would be. Chapter 5 shows you how to use EndNote, one example of reference management software.

Click the drop down below to review the terms learned from this chapter.

Copyright note:

  • The quotation from Pautasso, M 2013, ‘Ten simple rules for writing a literature review’, PLoS Computational Biology is use under a CC-BY licence. 
  • Content from the annotated article and tables are based on Schubert, MM, Astorino, TA & Azevedo, JJL 2013, ‘The effects of caffeinated ‘energy shots’ on time trial performance’, Nutrients, vol. 5, no. 6, pp. 2062–2075 (used under a CC-BY 3.0 licence ) and P ing, WC, Keong , CC & Bandyopadhyay, A 2010, ‘Effects of acute supplementation of caffeine on cardiorespiratory responses during endurance running in a hot and humid climate’, Indian Journal of Medical Research, vol. 132, pp. 36–41 (used under a CC-BY-NC-SA 4.0 licence ). 

Bain, A.R., Morrison, S.A., & Ainslie, P.N. (2014). Cerebral oxygenation and hyperthermia. Frontiers in Physiology, 5 , 92.

Pautasso, M. (2013). Ten simple rules for writing a literature review. PLoS Computational Biology, 9 (7), e1003149.

How To Do Science Copyright © 2022 by University of Southern Queensland is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , except where otherwise noted.

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How to Write a Good Scientific Literature Review

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Nowadays, there is a huge demand for scientific literature reviews as they are especially appreciated by scholars or researchers when designing their research proposals. While finding information is less of a problem to them, discerning which paper or publication has enough quality has become one of the biggest issues. Literature reviews narrow the current knowledge on a certain field and examine the latest publications’ strengths and weaknesses. This way, they are priceless tools not only for those who are starting their research, but also for all those interested in recent publications. To be useful, literature reviews must be written in a professional way with a clear structure. The amount of work needed to write a scientific literature review must be considered before starting one since the tasks required can overwhelm many if the working method is not the best.

Designing and Writing a Scientific Literature Review

Writing a scientific review implies both researching for relevant academic content and writing , however, writing without having a clear objective is a common mistake. Sometimes, studying the situation and defining the work’s system is so important and takes equally as much time as that required in writing the final result. Therefore, we suggest that you divide your path into three steps.

Define goals and a structure

Think about your target and narrow down your topic. If you don’t choose a well-defined topic, you can find yourself dealing with a wide subject and plenty of publications about it. Remember that researchers usually deal with really specific fields of study.

It is time to be a critic and locate only pertinent publications. While researching for content consider publications that were written 3 years ago at the most. Write notes and summarize the content of each paper as that will help you in the next step.

Time to write

Check some literature review examples to decide how to start writing a good literature review . When your goals and structure are defined, begin writing without forgetting your target at any moment.

Related: Conducting a literature survey? Wish to learn more about scientific misconduct? Check out this resourceful infographic.

Here you have a to-do list to help you write your review :

Review Article

  • A scientific literature review usually includes a title, abstract, index, introduction, corpus, bibliography, and appendices (if needed).
  • Present the problem clearly.
  • Mention the paper’s methodology, research methods, analysis, instruments, etc.
  • Present literature review examples that can help you express your ideas.
  • Remember to cite accurately.
  • Limit your bias
  • While summarizing also identify strengths and weaknesses as this is critical.

Scholars and researchers are usually the best candidates to write scientific literature reviews, not only because they are experts in a certain field, but also because they know the exigencies and needs that researchers have while writing research proposals or looking for information among thousands of academic papers. Therefore, considering your experience as a researcher can help you understand how to write a scientific literature review.

Have you faced challenges while drafting your first literature review? How do you think can these tips help you in acing your next literature review? Let us know in the comments section below! You can also visit our  Q&A forum  for frequently asked questions related to copyrights answered by our team that comprises eminent researchers and publication experts.

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Thank you for your information. It adds knowledge on critical review being a first time to do it, it helps a lot.

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How to Write a Research Paper | A Beginner's Guide

A research paper is a piece of academic writing that provides analysis, interpretation, and argument based on in-depth independent research.

Research papers are similar to academic essays , but they are usually longer and more detailed assignments, designed to assess not only your writing skills but also your skills in scholarly research. Writing a research paper requires you to demonstrate a strong knowledge of your topic, engage with a variety of sources, and make an original contribution to the debate.

This step-by-step guide takes you through the entire writing process, from understanding your assignment to proofreading your final draft.

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Table of contents

Understand the assignment, choose a research paper topic, conduct preliminary research, develop a thesis statement, create a research paper outline, write a first draft of the research paper, write the introduction, write a compelling body of text, write the conclusion, the second draft, the revision process, research paper checklist, free lecture slides.

Completing a research paper successfully means accomplishing the specific tasks set out for you. Before you start, make sure you thoroughly understanding the assignment task sheet:

  • Read it carefully, looking for anything confusing you might need to clarify with your professor.
  • Identify the assignment goal, deadline, length specifications, formatting, and submission method.
  • Make a bulleted list of the key points, then go back and cross completed items off as you’re writing.

Carefully consider your timeframe and word limit: be realistic, and plan enough time to research, write, and edit.

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how to start writing a scientific review paper

There are many ways to generate an idea for a research paper, from brainstorming with pen and paper to talking it through with a fellow student or professor.

You can try free writing, which involves taking a broad topic and writing continuously for two or three minutes to identify absolutely anything relevant that could be interesting.

You can also gain inspiration from other research. The discussion or recommendations sections of research papers often include ideas for other specific topics that require further examination.

Once you have a broad subject area, narrow it down to choose a topic that interests you, m eets the criteria of your assignment, and i s possible to research. Aim for ideas that are both original and specific:

  • A paper following the chronology of World War II would not be original or specific enough.
  • A paper on the experience of Danish citizens living close to the German border during World War II would be specific and could be original enough.

Note any discussions that seem important to the topic, and try to find an issue that you can focus your paper around. Use a variety of sources , including journals, books, and reliable websites, to ensure you do not miss anything glaring.

Do not only verify the ideas you have in mind, but look for sources that contradict your point of view.

  • Is there anything people seem to overlook in the sources you research?
  • Are there any heated debates you can address?
  • Do you have a unique take on your topic?
  • Have there been some recent developments that build on the extant research?

In this stage, you might find it helpful to formulate some research questions to help guide you. To write research questions, try to finish the following sentence: “I want to know how/what/why…”

A thesis statement is a statement of your central argument — it establishes the purpose and position of your paper. If you started with a research question, the thesis statement should answer it. It should also show what evidence and reasoning you’ll use to support that answer.

The thesis statement should be concise, contentious, and coherent. That means it should briefly summarize your argument in a sentence or two, make a claim that requires further evidence or analysis, and make a coherent point that relates to every part of the paper.

You will probably revise and refine the thesis statement as you do more research, but it can serve as a guide throughout the writing process. Every paragraph should aim to support and develop this central claim.

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A research paper outline is essentially a list of the key topics, arguments, and evidence you want to include, divided into sections with headings so that you know roughly what the paper will look like before you start writing.

A structure outline can help make the writing process much more efficient, so it’s worth dedicating some time to create one.

Your first draft won’t be perfect — you can polish later on. Your priorities at this stage are as follows:

  • Maintaining forward momentum — write now, perfect later.
  • Paying attention to clear organization and logical ordering of paragraphs and sentences, which will help when you come to the second draft.
  • Expressing your ideas as clearly as possible, so you know what you were trying to say when you come back to the text.

You do not need to start by writing the introduction. Begin where it feels most natural for you — some prefer to finish the most difficult sections first, while others choose to start with the easiest part. If you created an outline, use it as a map while you work.

Do not delete large sections of text. If you begin to dislike something you have written or find it doesn’t quite fit, move it to a different document, but don’t lose it completely — you never know if it might come in useful later.

Paragraph structure

Paragraphs are the basic building blocks of research papers. Each one should focus on a single claim or idea that helps to establish the overall argument or purpose of the paper.

Example paragraph

George Orwell’s 1946 essay “Politics and the English Language” has had an enduring impact on thought about the relationship between politics and language. This impact is particularly obvious in light of the various critical review articles that have recently referenced the essay. For example, consider Mark Falcoff’s 2009 article in The National Review Online, “The Perversion of Language; or, Orwell Revisited,” in which he analyzes several common words (“activist,” “civil-rights leader,” “diversity,” and more). Falcoff’s close analysis of the ambiguity built into political language intentionally mirrors Orwell’s own point-by-point analysis of the political language of his day. Even 63 years after its publication, Orwell’s essay is emulated by contemporary thinkers.

Citing sources

It’s also important to keep track of citations at this stage to avoid accidental plagiarism . Each time you use a source, make sure to take note of where the information came from.

You can use our free citation generators to automatically create citations and save your reference list as you go.

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The research paper introduction should address three questions: What, why, and how? After finishing the introduction, the reader should know what the paper is about, why it is worth reading, and how you’ll build your arguments.

What? Be specific about the topic of the paper, introduce the background, and define key terms or concepts.

Why? This is the most important, but also the most difficult, part of the introduction. Try to provide brief answers to the following questions: What new material or insight are you offering? What important issues does your essay help define or answer?

How? To let the reader know what to expect from the rest of the paper, the introduction should include a “map” of what will be discussed, briefly presenting the key elements of the paper in chronological order.

The major struggle faced by most writers is how to organize the information presented in the paper, which is one reason an outline is so useful. However, remember that the outline is only a guide and, when writing, you can be flexible with the order in which the information and arguments are presented.

One way to stay on track is to use your thesis statement and topic sentences . Check:

  • topic sentences against the thesis statement;
  • topic sentences against each other, for similarities and logical ordering;
  • and each sentence against the topic sentence of that paragraph.

Be aware of paragraphs that seem to cover the same things. If two paragraphs discuss something similar, they must approach that topic in different ways. Aim to create smooth transitions between sentences, paragraphs, and sections.

The research paper conclusion is designed to help your reader out of the paper’s argument, giving them a sense of finality.

Trace the course of the paper, emphasizing how it all comes together to prove your thesis statement. Give the paper a sense of finality by making sure the reader understands how you’ve settled the issues raised in the introduction.

You might also discuss the more general consequences of the argument, outline what the paper offers to future students of the topic, and suggest any questions the paper’s argument raises but cannot or does not try to answer.

You should not :

  • Offer new arguments or essential information
  • Take up any more space than necessary
  • Begin with stock phrases that signal you are ending the paper (e.g. “In conclusion”)

There are four main considerations when it comes to the second draft.

  • Check how your vision of the paper lines up with the first draft and, more importantly, that your paper still answers the assignment.
  • Identify any assumptions that might require (more substantial) justification, keeping your reader’s perspective foremost in mind. Remove these points if you cannot substantiate them further.
  • Be open to rearranging your ideas. Check whether any sections feel out of place and whether your ideas could be better organized.
  • If you find that old ideas do not fit as well as you anticipated, you should cut them out or condense them. You might also find that new and well-suited ideas occurred to you during the writing of the first draft — now is the time to make them part of the paper.

The goal during the revision and proofreading process is to ensure you have completed all the necessary tasks and that the paper is as well-articulated as possible. You can speed up the proofreading process by using the AI proofreader .

Global concerns

  • Confirm that your paper completes every task specified in your assignment sheet.
  • Check for logical organization and flow of paragraphs.
  • Check paragraphs against the introduction and thesis statement.

Fine-grained details

Check the content of each paragraph, making sure that:

  • each sentence helps support the topic sentence.
  • no unnecessary or irrelevant information is present.
  • all technical terms your audience might not know are identified.

Next, think about sentence structure , grammatical errors, and formatting . Check that you have correctly used transition words and phrases to show the connections between your ideas. Look for typos, cut unnecessary words, and check for consistency in aspects such as heading formatting and spellings .

Finally, you need to make sure your paper is correctly formatted according to the rules of the citation style you are using. For example, you might need to include an MLA heading  or create an APA title page .

Scribbr’s professional editors can help with the revision process with our award-winning proofreading services.

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Checklist: Research paper

I have followed all instructions in the assignment sheet.

My introduction presents my topic in an engaging way and provides necessary background information.

My introduction presents a clear, focused research problem and/or thesis statement .

My paper is logically organized using paragraphs and (if relevant) section headings .

Each paragraph is clearly focused on one central idea, expressed in a clear topic sentence .

Each paragraph is relevant to my research problem or thesis statement.

I have used appropriate transitions  to clarify the connections between sections, paragraphs, and sentences.

My conclusion provides a concise answer to the research question or emphasizes how the thesis has been supported.

My conclusion shows how my research has contributed to knowledge or understanding of my topic.

My conclusion does not present any new points or information essential to my argument.

I have provided an in-text citation every time I refer to ideas or information from a source.

I have included a reference list at the end of my paper, consistently formatted according to a specific citation style .

I have thoroughly revised my paper and addressed any feedback from my professor or supervisor.

I have followed all formatting guidelines (page numbers, headers, spacing, etc.).

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How to write a scientific review research paper.

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How do I write a scientific review research paper? originally appeared on Quora : the place to gain and share knowledge, empowering people to learn from others and better understand the world .

Answer by Barbara Robson , Research Scientist, on Quora :

How do I write a scientific review research paper?

I have written a few review papers, and this is my approach. There are doubtless others that are equally effective, and some of these will be faster, but the approach that I will suggest is one that is thorough and defensible.

First, make sure that you are an expert in the subject and aware of the recent literature on the topic you have in mind. Consider working with co-authors so that together your expertise in the area is broad and deep.

Next, read all the other review papers that have been published on related topics, or similar topics in related fields, over the previous two to three decades, to make sure that you understand what has been already done and to make sure that there is a gap in the existing reviews.

Then it is time to work out what question you will be trying to answer with your review. Some examples of questions that can be answered by review papers include:

  • What has changed in our understanding of this topic since the last review? What are the biggest challenges facing researchers in this field today? And, what are the most promising approaches to solving these challenges?
  • Is there enough evidence in the existing literature to decide which of two competing conceptual models or theories is most likely to be correct?
  • Is there enough evidence in the literature to justify a commonly held belief or assumption in this field?
  • How well have active researchers in this field adopted what are now considered best practices, and is this improving our scientific results?
  • Of a few methodologies used in this field, which has proven most successful or useful over time?
  • How applicable are ideas developed in one area (for instance, “in temperate rivers”) to another area (e.g. “tropical rivers”)?

You get the idea — you don’t have to pick one of these, but it is a good idea to frame your review around some question of which the answer is not obvious even to expert researchers in the field.

Once you have your question, start reading the literature to gather evidence. It is a good idea to do this in a systematic way to make sure that you are not cherry-picking the literature to support a pre-concieved idea or to favor the research of one particular group. Choose keywords carefully, choose a good database such as Web of Science, choose the time-frame that your review will cover, and read everything that is a match. Take notes and, if appropriate to your research question, keep track of your findings in a spreadsheet or database. You will not be citing everything that you read for your review, but it is a good idea to keep track of everything that you have read that matched your search criteria, and what you learned from it.

At some point during this reading, you will start preparing the outline for your review paper. Work out how you will structure the paper, what key points you want to highlight, and what the story is that you will be telling through your review. Often, good review papers will include figures that combine results from the literature that you have searched through to tell readers something new, either through new, collated representations of data that show new, emergent relationships, or through new conceptual models that will help others to think about the topic in a new way and structure future research. Plan what these figures will be in your paper.

Also think carefully about who your intended audience will be. Is it aimed at new (post)graduate students who are just getting into the field and need somewhere to start? Is it aimed at your fellow expert researchers in the field, whose thinking you would like to influence? Is it aimed at industry practitioners, who may not be able to read all the literature themselves, but need a good summary of the evidence and how it should influence their practice? Is it aimed at people in related fields who may be venturing into a new cross-disciplinary area? Know your goal and your audience and it should then be clear what to include in your review and what to leave out.

Finally, it is time to start writing. Like any other paper, this will need to have an Introduction, which explains what has been done before (for example, in previous reviews) and what has motivated your review paper (i.e. what question are you trying to answer, and for whom). It may have Methods and Results sections, particularly if you have taken a systemmatic and quantitative approach to your review, or it may be a more narrative review, divided into sections that help you tell the story and elucidate the topic. It should certainly have a Conclusions section: what should change as a result of what you have found and discussed in your review?

As with any paper, aim to write clearly and in a way that will be interesting for your intended audience. Aim to write in a way that makes it easy to find and understand your key messages, even for skim-readers. Aim to be concise but to back up everything you say with evidence.

Once you have this done and have asked a friendly colleague to look over it and give you feedback, you will be ready to submit the review to a good journal in your field. Make sure that it is a journal that does publish reviews, and consider sending the editor a query first if you are not sure whether they publish reviews that have not been solicited.

This question originally appeared on Quora - the place to gain and share knowledge, empowering people to learn from others and better understand the world. You can follow Quora on Twitter , Facebook , and Google+ . More questions:

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How to write your first research paper.

Writing a research manuscript is an intimidating process for many novice writers in the sciences. One of the stumbling blocks is the beginning of the process and creating the first draft. This paper presents guidelines on how to initiate the writing process and draft each section of a research manuscript. The paper discusses seven rules that allow the writer to prepare a well-structured and comprehensive manuscript for a publication submission. In addition, the author lists different strategies for successful revision. Each of those strategies represents a step in the revision process and should help the writer improve the quality of the manuscript. The paper could be considered a brief manual for publication.

It is late at night. You have been struggling with your project for a year. You generated an enormous amount of interesting data. Your pipette feels like an extension of your hand, and running western blots has become part of your daily routine, similar to brushing your teeth. Your colleagues think you are ready to write a paper, and your lab mates tease you about your “slow” writing progress. Yet days pass, and you cannot force yourself to sit down to write. You have not written anything for a while (lab reports do not count), and you feel you have lost your stamina. How does the writing process work? How can you fit your writing into a daily schedule packed with experiments? What section should you start with? What distinguishes a good research paper from a bad one? How should you revise your paper? These and many other questions buzz in your head and keep you stressed. As a result, you procrastinate. In this paper, I will discuss the issues related to the writing process of a scientific paper. Specifically, I will focus on the best approaches to start a scientific paper, tips for writing each section, and the best revision strategies.

1. Schedule your writing time in Outlook

Whether you have written 100 papers or you are struggling with your first, starting the process is the most difficult part unless you have a rigid writing schedule. Writing is hard. It is a very difficult process of intense concentration and brain work. As stated in Hayes’ framework for the study of writing: “It is a generative activity requiring motivation, and it is an intellectual activity requiring cognitive processes and memory” [ 1 ]. In his book How to Write a Lot: A Practical Guide to Productive Academic Writing , Paul Silvia says that for some, “it’s easier to embalm the dead than to write an article about it” [ 2 ]. Just as with any type of hard work, you will not succeed unless you practice regularly. If you have not done physical exercises for a year, only regular workouts can get you into good shape again. The same kind of regular exercises, or I call them “writing sessions,” are required to be a productive author. Choose from 1- to 2-hour blocks in your daily work schedule and consider them as non-cancellable appointments. When figuring out which blocks of time will be set for writing, you should select the time that works best for this type of work. For many people, mornings are more productive. One Yale University graduate student spent a semester writing from 8 a.m. to 9 a.m. when her lab was empty. At the end of the semester, she was amazed at how much she accomplished without even interrupting her regular lab hours. In addition, doing the hardest task first thing in the morning contributes to the sense of accomplishment during the rest of the day. This positive feeling spills over into our work and life and has a very positive effect on our overall attitude.

Rule 1: Create regular time blocks for writing as appointments in your calendar and keep these appointments.

2. start with an outline.

Now that you have scheduled time, you need to decide how to start writing. The best strategy is to start with an outline. This will not be an outline that you are used to, with Roman numerals for each section and neat parallel listing of topic sentences and supporting points. This outline will be similar to a template for your paper. Initially, the outline will form a structure for your paper; it will help generate ideas and formulate hypotheses. Following the advice of George M. Whitesides, “. . . start with a blank piece of paper, and write down, in any order, all important ideas that occur to you concerning the paper” [ 3 ]. Use Table 1 as a starting point for your outline. Include your visuals (figures, tables, formulas, equations, and algorithms), and list your findings. These will constitute the first level of your outline, which will eventually expand as you elaborate.

The next stage is to add context and structure. Here you will group all your ideas into sections: Introduction, Methods, Results, and Discussion/Conclusion ( Table 2 ). This step will help add coherence to your work and sift your ideas.

Now that you have expanded your outline, you are ready for the next step: discussing the ideas for your paper with your colleagues and mentor. Many universities have a writing center where graduate students can schedule individual consultations and receive assistance with their paper drafts. Getting feedback during early stages of your draft can save a lot of time. Talking through ideas allows people to conceptualize and organize thoughts to find their direction without wasting time on unnecessary writing. Outlining is the most effective way of communicating your ideas and exchanging thoughts. Moreover, it is also the best stage to decide to which publication you will submit the paper. Many people come up with three choices and discuss them with their mentors and colleagues. Having a list of journal priorities can help you quickly resubmit your paper if your paper is rejected.

Rule 2: Create a detailed outline and discuss it with your mentor and peers.

3. continue with drafts.

After you get enough feedback and decide on the journal you will submit to, the process of real writing begins. Copy your outline into a separate file and expand on each of the points, adding data and elaborating on the details. When you create the first draft, do not succumb to the temptation of editing. Do not slow down to choose a better word or better phrase; do not halt to improve your sentence structure. Pour your ideas into the paper and leave revision and editing for later. As Paul Silvia explains, “Revising while you generate text is like drinking decaffeinated coffee in the early morning: noble idea, wrong time” [ 2 ].

Many students complain that they are not productive writers because they experience writer’s block. Staring at an empty screen is frustrating, but your screen is not really empty: You have a template of your article, and all you need to do is fill in the blanks. Indeed, writer’s block is a logical fallacy for a scientist ― it is just an excuse to procrastinate. When scientists start writing a research paper, they already have their files with data, lab notes with materials and experimental designs, some visuals, and tables with results. All they need to do is scrutinize these pieces and put them together into a comprehensive paper.

3.1. Starting with Materials and Methods

If you still struggle with starting a paper, then write the Materials and Methods section first. Since you have all your notes, it should not be problematic for you to describe the experimental design and procedures. Your most important goal in this section is to be as explicit as possible by providing enough detail and references. In the end, the purpose of this section is to allow other researchers to evaluate and repeat your work. So do not run into the same problems as the writers of the sentences in (1):

1a. Bacteria were pelleted by centrifugation. 1b. To isolate T cells, lymph nodes were collected.

As you can see, crucial pieces of information are missing: the speed of centrifuging your bacteria, the time, and the temperature in (1a); the source of lymph nodes for collection in (b). The sentences can be improved when information is added, as in (2a) and (2b), respectfully:

2a. Bacteria were pelleted by centrifugation at 3000g for 15 min at 25°C. 2b. To isolate T cells, mediastinal and mesenteric lymph nodes from Balb/c mice were collected at day 7 after immunization with ovabumin.

If your method has previously been published and is well-known, then you should provide only the literature reference, as in (3a). If your method is unpublished, then you need to make sure you provide all essential details, as in (3b).

3a. Stem cells were isolated, according to Johnson [23]. 3b. Stem cells were isolated using biotinylated carbon nanotubes coated with anti-CD34 antibodies.

Furthermore, cohesion and fluency are crucial in this section. One of the malpractices resulting in disrupted fluency is switching from passive voice to active and vice versa within the same paragraph, as shown in (4). This switching misleads and distracts the reader.

4. Behavioral computer-based experiments of Study 1 were programmed by using E-Prime. We took ratings of enjoyment, mood, and arousal as the patients listened to preferred pleasant music and unpreferred music by using Visual Analogue Scales (SI Methods). The preferred and unpreferred status of the music was operationalized along a continuum of pleasantness [ 4 ].

The problem with (4) is that the reader has to switch from the point of view of the experiment (passive voice) to the point of view of the experimenter (active voice). This switch causes confusion about the performer of the actions in the first and the third sentences. To improve the coherence and fluency of the paragraph above, you should be consistent in choosing the point of view: first person “we” or passive voice [ 5 ]. Let’s consider two revised examples in (5).

5a. We programmed behavioral computer-based experiments of Study 1 by using E-Prime. We took ratings of enjoyment, mood, and arousal by using Visual Analogue Scales (SI Methods) as the patients listened to preferred pleasant music and unpreferred music. We operationalized the preferred and unpreferred status of the music along a continuum of pleasantness. 5b. Behavioral computer-based experiments of Study 1 were programmed by using E-Prime. Ratings of enjoyment, mood, and arousal were taken as the patients listened to preferred pleasant music and unpreferred music by using Visual Analogue Scales (SI Methods). The preferred and unpreferred status of the music was operationalized along a continuum of pleasantness.

If you choose the point of view of the experimenter, then you may end up with repetitive “we did this” sentences. For many readers, paragraphs with sentences all beginning with “we” may also sound disruptive. So if you choose active sentences, you need to keep the number of “we” subjects to a minimum and vary the beginnings of the sentences [ 6 ].

Interestingly, recent studies have reported that the Materials and Methods section is the only section in research papers in which passive voice predominantly overrides the use of the active voice [ 5 , 7 , 8 , 9 ]. For example, Martínez shows a significant drop in active voice use in the Methods sections based on the corpus of 1 million words of experimental full text research articles in the biological sciences [ 7 ]. According to the author, the active voice patterned with “we” is used only as a tool to reveal personal responsibility for the procedural decisions in designing and performing experimental work. This means that while all other sections of the research paper use active voice, passive voice is still the most predominant in Materials and Methods sections.

Writing Materials and Methods sections is a meticulous and time consuming task requiring extreme accuracy and clarity. This is why when you complete your draft, you should ask for as much feedback from your colleagues as possible. Numerous readers of this section will help you identify the missing links and improve the technical style of this section.

Rule 3: Be meticulous and accurate in describing the Materials and Methods. Do not change the point of view within one paragraph.

3.2. writing results section.

For many authors, writing the Results section is more intimidating than writing the Materials and Methods section . If people are interested in your paper, they are interested in your results. That is why it is vital to use all your writing skills to objectively present your key findings in an orderly and logical sequence using illustrative materials and text.

Your Results should be organized into different segments or subsections where each one presents the purpose of the experiment, your experimental approach, data including text and visuals (tables, figures, schematics, algorithms, and formulas), and data commentary. For most journals, your data commentary will include a meaningful summary of the data presented in the visuals and an explanation of the most significant findings. This data presentation should not repeat the data in the visuals, but rather highlight the most important points. In the “standard” research paper approach, your Results section should exclude data interpretation, leaving it for the Discussion section. However, interpretations gradually and secretly creep into research papers: “Reducing the data, generalizing from the data, and highlighting scientific cases are all highly interpretive processes. It should be clear by now that we do not let the data speak for themselves in research reports; in summarizing our results, we interpret them for the reader” [ 10 ]. As a result, many journals including the Journal of Experimental Medicine and the Journal of Clinical Investigation use joint Results/Discussion sections, where results are immediately followed by interpretations.

Another important aspect of this section is to create a comprehensive and supported argument or a well-researched case. This means that you should be selective in presenting data and choose only those experimental details that are essential for your reader to understand your findings. You might have conducted an experiment 20 times and collected numerous records, but this does not mean that you should present all those records in your paper. You need to distinguish your results from your data and be able to discard excessive experimental details that could distract and confuse the reader. However, creating a picture or an argument should not be confused with data manipulation or falsification, which is a willful distortion of data and results. If some of your findings contradict your ideas, you have to mention this and find a plausible explanation for the contradiction.

In addition, your text should not include irrelevant and peripheral information, including overview sentences, as in (6).

6. To show our results, we first introduce all components of experimental system and then describe the outcome of infections.

Indeed, wordiness convolutes your sentences and conceals your ideas from readers. One common source of wordiness is unnecessary intensifiers. Adverbial intensifiers such as “clearly,” “essential,” “quite,” “basically,” “rather,” “fairly,” “really,” and “virtually” not only add verbosity to your sentences, but also lower your results’ credibility. They appeal to the reader’s emotions but lower objectivity, as in the common examples in (7):

7a. Table 3 clearly shows that … 7b. It is obvious from figure 4 that …

Another source of wordiness is nominalizations, i.e., nouns derived from verbs and adjectives paired with weak verbs including “be,” “have,” “do,” “make,” “cause,” “provide,” and “get” and constructions such as “there is/are.”

8a. We tested the hypothesis that there is a disruption of membrane asymmetry. 8b. In this paper we provide an argument that stem cells repopulate injured organs.

In the sentences above, the abstract nominalizations “disruption” and “argument” do not contribute to the clarity of the sentences, but rather clutter them with useless vocabulary that distracts from the meaning. To improve your sentences, avoid unnecessary nominalizations and change passive verbs and constructions into active and direct sentences.

9a. We tested the hypothesis that the membrane asymmetry is disrupted. 9b. In this paper we argue that stem cells repopulate injured organs.

Your Results section is the heart of your paper, representing a year or more of your daily research. So lead your reader through your story by writing direct, concise, and clear sentences.

Rule 4: Be clear, concise, and objective in describing your Results.

3.3. now it is time for your introduction.

Now that you are almost half through drafting your research paper, it is time to update your outline. While describing your Methods and Results, many of you diverged from the original outline and re-focused your ideas. So before you move on to create your Introduction, re-read your Methods and Results sections and change your outline to match your research focus. The updated outline will help you review the general picture of your paper, the topic, the main idea, and the purpose, which are all important for writing your introduction.

The best way to structure your introduction is to follow the three-move approach shown in Table 3 .

Adapted from Swales and Feak [ 11 ].

The moves and information from your outline can help to create your Introduction efficiently and without missing steps. These moves are traffic signs that lead the reader through the road of your ideas. Each move plays an important role in your paper and should be presented with deep thought and care. When you establish the territory, you place your research in context and highlight the importance of your research topic. By finding the niche, you outline the scope of your research problem and enter the scientific dialogue. The final move, “occupying the niche,” is where you explain your research in a nutshell and highlight your paper’s significance. The three moves allow your readers to evaluate their interest in your paper and play a significant role in the paper review process, determining your paper reviewers.

Some academic writers assume that the reader “should follow the paper” to find the answers about your methodology and your findings. As a result, many novice writers do not present their experimental approach and the major findings, wrongly believing that the reader will locate the necessary information later while reading the subsequent sections [ 5 ]. However, this “suspense” approach is not appropriate for scientific writing. To interest the reader, scientific authors should be direct and straightforward and present informative one-sentence summaries of the results and the approach.

Another problem is that writers understate the significance of the Introduction. Many new researchers mistakenly think that all their readers understand the importance of the research question and omit this part. However, this assumption is faulty because the purpose of the section is not to evaluate the importance of the research question in general. The goal is to present the importance of your research contribution and your findings. Therefore, you should be explicit and clear in describing the benefit of the paper.

The Introduction should not be long. Indeed, for most journals, this is a very brief section of about 250 to 600 words, but it might be the most difficult section due to its importance.

Rule 5: Interest your reader in the Introduction section by signalling all its elements and stating the novelty of the work.

3.4. discussion of the results.

For many scientists, writing a Discussion section is as scary as starting a paper. Most of the fear comes from the variation in the section. Since every paper has its unique results and findings, the Discussion section differs in its length, shape, and structure. However, some general principles of writing this section still exist. Knowing these rules, or “moves,” can change your attitude about this section and help you create a comprehensive interpretation of your results.

The purpose of the Discussion section is to place your findings in the research context and “to explain the meaning of the findings and why they are important, without appearing arrogant, condescending, or patronizing” [ 11 ]. The structure of the first two moves is almost a mirror reflection of the one in the Introduction. In the Introduction, you zoom in from general to specific and from the background to your research question; in the Discussion section, you zoom out from the summary of your findings to the research context, as shown in Table 4 .

Adapted from Swales and Feak and Hess [ 11 , 12 ].

The biggest challenge for many writers is the opening paragraph of the Discussion section. Following the moves in Table 1 , the best choice is to start with the study’s major findings that provide the answer to the research question in your Introduction. The most common starting phrases are “Our findings demonstrate . . .,” or “In this study, we have shown that . . .,” or “Our results suggest . . .” In some cases, however, reminding the reader about the research question or even providing a brief context and then stating the answer would make more sense. This is important in those cases where the researcher presents a number of findings or where more than one research question was presented. Your summary of the study’s major findings should be followed by your presentation of the importance of these findings. One of the most frequent mistakes of the novice writer is to assume the importance of his findings. Even if the importance is clear to you, it may not be obvious to your reader. Digesting the findings and their importance to your reader is as crucial as stating your research question.

Another useful strategy is to be proactive in the first move by predicting and commenting on the alternative explanations of the results. Addressing potential doubts will save you from painful comments about the wrong interpretation of your results and will present you as a thoughtful and considerate researcher. Moreover, the evaluation of the alternative explanations might help you create a logical step to the next move of the discussion section: the research context.

The goal of the research context move is to show how your findings fit into the general picture of the current research and how you contribute to the existing knowledge on the topic. This is also the place to discuss any discrepancies and unexpected findings that may otherwise distort the general picture of your paper. Moreover, outlining the scope of your research by showing the limitations, weaknesses, and assumptions is essential and adds modesty to your image as a scientist. However, make sure that you do not end your paper with the problems that override your findings. Try to suggest feasible explanations and solutions.

If your submission does not require a separate Conclusion section, then adding another paragraph about the “take-home message” is a must. This should be a general statement reiterating your answer to the research question and adding its scientific implications, practical application, or advice.

Just as in all other sections of your paper, the clear and precise language and concise comprehensive sentences are vital. However, in addition to that, your writing should convey confidence and authority. The easiest way to illustrate your tone is to use the active voice and the first person pronouns. Accompanied by clarity and succinctness, these tools are the best to convince your readers of your point and your ideas.

Rule 6: Present the principles, relationships, and generalizations in a concise and convincing tone.

4. choosing the best working revision strategies.

Now that you have created the first draft, your attitude toward your writing should have improved. Moreover, you should feel more confident that you are able to accomplish your project and submit your paper within a reasonable timeframe. You also have worked out your writing schedule and followed it precisely. Do not stop ― you are only at the midpoint from your destination. Just as the best and most precious diamond is no more than an unattractive stone recognized only by trained professionals, your ideas and your results may go unnoticed if they are not polished and brushed. Despite your attempts to present your ideas in a logical and comprehensive way, first drafts are frequently a mess. Use the advice of Paul Silvia: “Your first drafts should sound like they were hastily translated from Icelandic by a non-native speaker” [ 2 ]. The degree of your success will depend on how you are able to revise and edit your paper.

The revision can be done at the macrostructure and the microstructure levels [ 13 ]. The macrostructure revision includes the revision of the organization, content, and flow. The microstructure level includes individual words, sentence structure, grammar, punctuation, and spelling.

The best way to approach the macrostructure revision is through the outline of the ideas in your paper. The last time you updated your outline was before writing the Introduction and the Discussion. Now that you have the beginning and the conclusion, you can take a bird’s-eye view of the whole paper. The outline will allow you to see if the ideas of your paper are coherently structured, if your results are logically built, and if the discussion is linked to the research question in the Introduction. You will be able to see if something is missing in any of the sections or if you need to rearrange your information to make your point.

The next step is to revise each of the sections starting from the beginning. Ideally, you should limit yourself to working on small sections of about five pages at a time [ 14 ]. After these short sections, your eyes get used to your writing and your efficiency in spotting problems decreases. When reading for content and organization, you should control your urge to edit your paper for sentence structure and grammar and focus only on the flow of your ideas and logic of your presentation. Experienced researchers tend to make almost three times the number of changes to meaning than novice writers [ 15 , 16 ]. Revising is a difficult but useful skill, which academic writers obtain with years of practice.

In contrast to the macrostructure revision, which is a linear process and is done usually through a detailed outline and by sections, microstructure revision is a non-linear process. While the goal of the macrostructure revision is to analyze your ideas and their logic, the goal of the microstructure editing is to scrutinize the form of your ideas: your paragraphs, sentences, and words. You do not need and are not recommended to follow the order of the paper to perform this type of revision. You can start from the end or from different sections. You can even revise by reading sentences backward, sentence by sentence and word by word.

One of the microstructure revision strategies frequently used during writing center consultations is to read the paper aloud [ 17 ]. You may read aloud to yourself, to a tape recorder, or to a colleague or friend. When reading and listening to your paper, you are more likely to notice the places where the fluency is disrupted and where you stumble because of a very long and unclear sentence or a wrong connector.

Another revision strategy is to learn your common errors and to do a targeted search for them [ 13 ]. All writers have a set of problems that are specific to them, i.e., their writing idiosyncrasies. Remembering these problems is as important for an academic writer as remembering your friends’ birthdays. Create a list of these idiosyncrasies and run a search for these problems using your word processor. If your problem is demonstrative pronouns without summary words, then search for “this/these/those” in your text and check if you used the word appropriately. If you have a problem with intensifiers, then search for “really” or “very” and delete them from the text. The same targeted search can be done to eliminate wordiness. Searching for “there is/are” or “and” can help you avoid the bulky sentences.

The final strategy is working with a hard copy and a pencil. Print a double space copy with font size 14 and re-read your paper in several steps. Try reading your paper line by line with the rest of the text covered with a piece of paper. When you are forced to see only a small portion of your writing, you are less likely to get distracted and are more likely to notice problems. You will end up spotting more unnecessary words, wrongly worded phrases, or unparallel constructions.

After you apply all these strategies, you are ready to share your writing with your friends, colleagues, and a writing advisor in the writing center. Get as much feedback as you can, especially from non-specialists in your field. Patiently listen to what others say to you ― you are not expected to defend your writing or explain what you wanted to say. You may decide what you want to change and how after you receive the feedback and sort it in your head. Even though some researchers make the revision an endless process and can hardly stop after a 14th draft; having from five to seven drafts of your paper is a norm in the sciences. If you can’t stop revising, then set a deadline for yourself and stick to it. Deadlines always help.

Rule 7: Revise your paper at the macrostructure and the microstructure level using different strategies and techniques. Receive feedback and revise again.

5. it is time to submit.

It is late at night again. You are still in your lab finishing revisions and getting ready to submit your paper. You feel happy ― you have finally finished a year’s worth of work. You will submit your paper tomorrow, and regardless of the outcome, you know that you can do it. If one journal does not take your paper, you will take advantage of the feedback and resubmit again. You will have a publication, and this is the most important achievement.

What is even more important is that you have your scheduled writing time that you are going to keep for your future publications, for reading and taking notes, for writing grants, and for reviewing papers. You are not going to lose stamina this time, and you will become a productive scientist. But for now, let’s celebrate the end of the paper.

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COMMENTS

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